4-(Pyridin-3-yl)phenylboronic acid, chemical formula C11H9BNO2, is an organic boron compound. The following is a description of its nature, use, formulation and safety information:
Nature:
4-(Pyridin-3-yl)phenylboronic acid is a solid, soluble in organic solvents such as ethanol and dimethylformamide. It has good thermal stability and is not easy to decompose.
Use:
4-(Pyridin-3-yl)phenylboronic acid is commonly used as a reagent in organic synthesis, especially in metal-catalyzed reactions. It can be used as a ligand to form a complex with a metal catalyst to improve the efficiency and selectivity of the catalytic reaction.
Method:
The method for preparing 4-(Pyridin-3-yl)phenylboronic acid is mainly obtained by the reaction of phenylboronic acid with 3-pyridine. In General, Phenylboronic acid is reacted with 3-pyridine at a certain temperature, and the target product is obtained through the steps of reaction, separation and purification.
Safety Information:
4-(Pyridin-3-yl)phenylboronic acid is relatively safe under normal circumstances, but the following matters still need to be paid attention:
-Wear protective equipment such as gloves, glasses and lab coats to avoid contact with skin and eyes.
-Avoid inhaling its dust or vapors. The compound should be handled with good ventilation and a protective mask should be provided if necessary.
-should be stored away from the fire and oxidant, avoid contact with high temperature and open flame.
-In case of accidental splashing into eyes or skin, rinse immediately with plenty of water and seek medical help.
-When using and storing, follow the relevant safety instructions and place it out of the reach of children.